Premium
Powder X‐Ray Diffraction Investigation of Xylazine Hydrochloride Solid Phase Transformation Kinetics
Author(s) -
KrūkleBērziņa Kristīne,
Actiņš Andris
Publication year - 2014
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/kin.20839
Subject(s) - chemistry , kinetics , nucleation , phase transition , thermodynamics , powder diffraction , phase (matter) , diffraction , reaction rate constant , equation of state , avrami equation , crystallography , organic chemistry , physics , crystallization of polymers , quantum mechanics , optics
The kinetics of the solid‐state phase transformation of xylazine hydrochloride form X to A has been investigated using powder X‐ray diffraction and differential thermal analysis. Three different kinetic models have been used to describe transition kinetics: the Avrami–Erofeev equation, the Cardew equation, and the methodology for simulation of solid‐state phase transition kinetics by the combination of nucleation and nuclei growth processes. The latter has been recently developed and has been tested in this paper for the case of a real solid‐state transition. The relative humidity, mechanical pressure, temperature, and sample‐preparation effect on phase‐transition kinetics have been investigated, and rate constant changes have been analyzed.