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Comparative study of the cationic surfactants and their influence on the alkaline hydrolysis of acetylsalicylic acid
Author(s) -
Kumar Birendra,
Ghosh Kallol K.,
Dafonte P. Rodriquez
Publication year - 2011
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/kin.20515
Subject(s) - chemistry , cationic polymerization , pulmonary surfactant , bromide , alkaline hydrolysis , hydroxide , hydrolysis , sodium hydroxide , inorganic chemistry , cetylpyridinium chloride , reaction rate constant , nuclear chemistry , kinetics , polymer chemistry , organic chemistry , biochemistry , physics , quantum mechanics
A kinetic study of the reaction of acetylsalicylic acid (aspirin) with sodium hydroxide has been studied in the presence of some conventional and novel cationic surfactants. The pseudo‐first‐order rate constant increases with the surfactant concentration initially and then decreases. In comparison to conventional cationic surfactants, i.e., cetyltrimethylammonium bromide and cetylpyridinium bromide, novel alkyldiethylethanolammonium bromide (R = C 16 ) surfactant accelerated the alkaline hydrolysis significantly. The pseudophase ion‐exchange model has been applied to fit the experimental results. Activation parameters have also been evaluated. © 2010 Wiley Periodicals, Inc. Int J Chem Kinet 43: 1–8, 2011