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Kinetics and reactivity of substituted anilines with 2‐chloro‐5‐nitropyridine in dimethyl sulfoxide and dimethyl formamide
Author(s) -
ElBardan Ali A.,
ElSubruiti Gehan M.,
ElHegazy Fatma ElZahraa M.,
Hamed Ezzat A.
Publication year - 2002
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/kin.10053
Subject(s) - dimethyl sulfoxide , chemistry , dimethyl formamide , formamide , kinetics , reactivity (psychology) , medicinal chemistry , base (topology) , amine gas treating , dimethyl sulfate , organic chemistry , solvent , medicine , mathematical analysis , physics , alternative medicine , mathematics , pathology , quantum mechanics
The kinetics of the reaction of substituted anilines with 2‐chloro‐5‐nitropyridine were studied in dimethyl sulfonide (DMSO) and dimethyl formamide (DMF) at different amine concentrations and temperatures in the range 45–60°C. In both solvents the reaction was not a base‐catalyzed one. A plot of Δ H # versus Δ S # for the reaction in DMSO and DMF gave good straight lines with isokinetic temperatures 128°C and 105°C, respectively. Good linear relationships were obtained from the plots of log k 1 against σ° values at all temperatures with negative ρ values (−1.63 to −1.28 in DMSO) and (−1.26 to −0.90 in DMF). © 2002 Wiley Periodicals, Inc. Int J Chem Kinet 34: 645–650, 2002