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Value of Ultrasound in Diagnosing Perforation of Congenital Choledochal Cysts in Children
Author(s) -
Xin Yue,
Wang Xiao Man,
Wang Yu,
Hu Yan Xiu,
Jia Li Qun
Publication year - 2021
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.1002/jum.15604
Subject(s) - medicine , choledochal cysts , perforation , receiver operating characteristic , ultrasound , vomiting , abdominal pain , clinical significance , radiology , surgery , retrospective cohort study , cyst , materials science , metallurgy , punching
Objectives This study aimed to investigate the diagnostic value of ultrasound in children with perforation of congenital choledochal cysts. Methods Eligible patients recruited from January 2004 to December 2018 in our hospital were enrolled in this retrospective study. A total of 59 cases of congenital choledochal cysts with perforation were defined as the perforation group, and 100 cases of congenital choledochal cysts without perforation with similar symptoms were defined as the control group. Clinical features were analyzed and compared between the groups. The differential efficacy of varied diagnostic criteria was evaluated by a receiver operating characteristic analysis. Results Significant differences were found between the groups with respect to clinical characteristics (abdominal pain, vomiting, fever, and abdominal distention; all P < .01) and the disease onset age ( P < .001), but the diagnostic efficacy of both was poor (both areas under the curve, <0.7). The interruption of bile duct continuity only occurred in the perforation group with high specificity of 100% but poor sensitivity of 18.6%. The discrimination of combined features was significantly better (area under the curve, 0.936) than that of the disease onset age and clinical characteristics, with observed sensitivity and specificity of 93.2% and 94.0%, respectively. Conclusions Using specific features, ultrasound can effectively diagnose perforation of a congenital choledochal cyst in children.