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Affective disorders, DST, and treatment in PTSD patients: Clinical observations
Author(s) -
Olivera Arturo A.,
Fero David
Publication year - 1990
Publication title -
journal of traumatic stress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.259
H-Index - 134
eISSN - 1573-6598
pISSN - 0894-9867
DOI - 10.1002/jts.2490030309
Subject(s) - depression (economics) , psychology , psychiatry , traumatic stress , bipolar disorder , incidence (geometry) , clinical psychology , cognition , economics , macroeconomics , physics , optics
A study of 109 chronic, post‐traumatic stress disorder patients found 65 suffered current major affective disorders. Of these 65, 84.8% had major depression and 15.2% had bipolar disorder. Nonsuppression of the DST occurred only in those cases with concurrent major affective disorder, the incidence of nonsuppression was 32.3%. Treatment effectively attained clinical improvement and conversion of nonsuppressor to suppressor state in these cases. The DST, cortisol suppression index, and inhibition of cortisol production index were useful to support the clinical diagnosis of major affective disorders in post‐traumatic stress disorder patients, in an exclusively clinical setting.

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