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Menstrual Cycle Effects on Psychological Symptoms in Women With PTSD
Author(s) -
Nillni Yael I.,
Pineles Suzanne L.,
Patton Samantha C.,
Rouse Matthew H.,
Sawyer Alice T.,
Rasmusson Ann M.
Publication year - 2015
Publication title -
journal of traumatic stress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.259
H-Index - 134
eISSN - 1573-6598
pISSN - 0894-9867
DOI - 10.1002/jts.21984
Subject(s) - menstrual cycle , anxiety , follicular phase , psychology , clinical psychology , depression (economics) , menstruation , psychiatry , medicine , hormone , economics , macroeconomics
The menstrual cycle has been implicated as a sex‐specific biological process influencing psychological symptoms across a variety of disorders. Limited research exists regarding the role of the menstrual cycle in psychological symptoms among women with posttraumatic stress disorder (PTSD). The current study examined the severity of a broad range of psychological symptoms in both the early follicular (Days 2–6) and midluteal (6–10 days postlutenizing hormone surge) phases of the menstrual cycle in a sample of trauma‐exposed women with and without PTSD ( N = 49). In the sample overall, total psychological symptoms ( d = 0.63), as well as depression ( d = 0.81) and phobic anxiety ( d = 0.81) symptoms, specifically, were increased in the early follicular compared to midluteal phase. The impact of menstrual cycle phase on phobic anxiety was modified by a significant PTSD × Menstrual Phase interaction ( d = 0.63). Women with PTSD reported more severe phobic anxiety during the early follicular versus midluteal phase, whereas phobic anxiety did not differ across the menstrual cycle in women without PTSD. Thus, the menstrual cycle appears to impact fear‐related symptoms in women with PTSD. The clinical implications of the findings and future research directions are discussed.