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Electromembrane extraction in microfluidic formats
Author(s) -
Hansen Frederik André,
Petersen Nickolaj Jacob,
Kutter Jörg P.,
PedersenBjergaard Stig
Publication year - 2022
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.202100603
Subject(s) - microfluidics , extraction (chemistry) , analyte , computer science , lab on a chip , data extraction , nanotechnology , data science , process engineering , chromatography , chemistry , engineering , materials science , biochemistry , medline
Electromembrane extraction is a microextraction technique where charged analytes are extracted across a supported liquid membrane and selectively isolated from the sample based on an electrical field. Since the introduction in 2006, there has been continuously increasing interest in electromembrane extraction, and currently close to 50 new articles are published per year. Electromembrane extraction can be performed in different technical configurations, based on standard laboratory glass vials or 96‐well plate systems, and applications are typically related to pharmaceutical, environmental, and food and beverages analysis. In addition to this, conceptual research has developed electromembrane extraction into different milli‐ and microfluidic formats. These are much more early‐stage activities, but applications among others related to organ‐on‐chip systems and smartphone detection indicate unique perspectives. To stimulate more research in this direction, the current article reviews the scientific literature on electromembrane extraction in milli‐ and microfluidic formats. About 20 original research articles have been published on this subject so far, and these are discussed critically in the following. Based on this and the authors own experiences with the topic, we discuss perspectives, challenges, and future research.