Premium
Front Cover: Supercritical fluid chromatography in chiral separations: Evaluation of equivalency of polysaccharide stationary phases
Author(s) -
Jakubec Pavel,
Douša Michal,
Nováková Lucie
Publication year - 2020
Publication title -
journal of separation science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.202070121
Subject(s) - supercritical fluid chromatography , supercritical fluid , methanol , chemistry , chromatography , moiety , chiral column chromatography , cellulose , chiral stationary phase , high performance liquid chromatography , organic chemistry
DOI: 10.1002/jssc.202000085 The cover picture shows the importance of the supercritical fluid chromatography (SFC) method for fast and efficient chiral separations. An extensive screening of CO 2 based mobile phases comparing a variety of modifiers/additives has been carried out using cellulose and amylose chiral stationary phases with the tris(3,5‐dimethylphenylcarbamate) moiety. Combined additives in methanol or isopropanol have shown the best potential for SFC chiral separations. The evaluation of the same stationary phases from different manufacturers has shown an important degree of non‐equivalence.