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Molecularly imprinted polymers in miniaturized extraction and separation devices
Author(s) -
Bouvarel Thomas,
Delaunay Nathalie,
Pichon Valérie
Publication year - 2021
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.202001223
Subject(s) - molecularly imprinted polymer , miniaturization , electrochromatography , polymer , materials science , chromatography , nanotechnology , solid phase extraction , sample preparation , polymerization , extraction (chemistry) , capillary electrochromatography , stationary phase , chemistry , catalysis , organic chemistry , composite material , selectivity
Molecularly imprinted polymers are highly selective and cost‐effective materials, which have attracted significant interest in various areas such as sample pretreatment and chromatographic and electrophoretic separations. This review aims to present the state of the art concerning the miniaturization of these materials in order to meet the societal demand for reliable, fast, cheap, and solvent/sample saving analyses. The polymerization route specificities for the production of miniaturized molecularly imprinted polymers in capillaries or chip channels, such as open tubular, packed particles, magnetic nanoparticles, and in situ imprinted monoliths, are investigated. Their performances as selective supports in solid phase extraction and as stationary phases in electrochromatography and liquid chromatography, as well as their possible perspectives are discussed.