z-logo
Premium
Chemical profiling and multicomponents quantitative analysis of Panzerina lanata by ultra‐fast liquid chromatography with tandem mass spectrometry
Author(s) -
Mi Yingying,
Zheng Wei,
Zhao Xiangpei,
Zhang Xun,
Yang Kang,
Shen Gangyi,
Liu Weizhi,
Li Wenrui,
Ma Baiping,
Zhu Dan
Publication year - 2021
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.202000944
Subject(s) - chromatography , chemistry , mass spectrometry , tandem mass spectrometry , quadrupole time of flight , quantitative analysis (chemistry) , high performance liquid chromatography , liquid chromatography–mass spectrometry
Panzerina lanata is a Chinese medicine with the bioactivity of detumescence and detoxification. In this study, novel qualitative and quantitative methods were established by ultra‐high performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry and ultra‐high‐performance liquid chromatography‐triple quadrupole linear ion trap mass spectrometry, respectively. As a result, 20 compounds were identified or tentatively characterized including flavonoids, organic acids, alkaloids, and lignans, five of which were identified for the first time based on the reference standards. The quantitative approach exhibited good linearity ( R 2  > 0.995), precision (RSDs < 4.97%), stability (RSDs < 4.77%), and recovery (96.04‐104.14%). Afterward, this method was implemented to determine 11 flavonoids in four batches of P. lanata . Among them, seven compounds were quantified for the first time. Narcissin was abundant in each batch of P. lanata (average of 10.890‐14.230 mg/g) with the highest quantities. The results provide valuable information for quality evaluation.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here