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β‐Cyclodextrin coupled to graphene oxide supported on aminopropyl silica as a sorbent material for determination of isoflavones
Author(s) -
da Silva Luis Felipe,
Lanças Fernando Mauro
Publication year - 2020
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.202000598
Subject(s) - sorbent , daidzein , detection limit , graphene , chromatography , formononetin , cyclodextrin , selectivity , chemistry , sorption , materials science , analytical chemistry (journal) , adsorption , genistein , organic chemistry , nanotechnology , medicine , catalysis
β‐Cyclodextrin, coupled to graphene oxide supported on aminopropyl silica, was synthesized and characterized. This material was combined with microextraction by packed sorbent to act as the sample preparation step. The analytical method optimization was carried out by employing experimental design and had its figures of merit determined. The resulting linearity ranged from 1.0 to 200 μg/L for daidzein, from 2.0 to 200 μg/L for genistein, from 3.0 to 200 μg/L for formononetin, and from 2.0 to 200 μg/L for biochanin A with all R 2 values above 0.993 and limit of quantification ranging from 0.5 to 1.5 μg/L. The accuracy ranged from 93.3 to 123.3%, and intraday and interday precision reported by the relative standard deviations were <16%. This work aimed to synthesize and evaluate cyclodextrins coupled to graphene‐based sorbents to be used as a high sorption capacity and selective sorbent for sample preparation of complex matrices using microextraction techniques. The synthesized material kept the high absorption characteristic of graphene‐based materials while maintaining the cyclodextrins’ selectivity to extract the target analyte. Four isoflavones were determined in soy‐based juice samples from the local market, confirming the excellent performance of the proposed method.