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Full use of the liquid nature of the stationary phase: The development of elution‐extrusion counter current chromatography
Author(s) -
Sun Xiao,
Pei Dong,
Duan WenDa,
Liu JianFei,
Di DuoLong,
Huang XinYi
Publication year - 2020
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.202000341
Subject(s) - elution , extrusion , chromatography , countercurrent chromatography , chemistry , current (fluid) , column chromatography , materials science , engineering , metallurgy , electrical engineering
Elution‐extrusion counter current chromatography extrudes the most solute retained in the column with the highest possible peak resolution. It can greatly improve the hydrophobic window. In recent years, elution‐extrusion counter current chromatography has received extensive attention in the separation of complex samples. This article first reviews the development and application of elution‐extrusion counter current chromatography, including its origin, mechanism, advantages and disadvantages, and some representative applications. At the same time, this review also shared our visions and ideas on how to improve the elution‐extrusion mode. This article aims to provide certain reference for the research of this technology.