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Preparation of boronate‐functionalized surface molecularly imprinted polymer microspheres with polydopamine coating for specific recognition and separation of glycoside template
Author(s) -
Pan Ting,
Lin Yali,
Wu Quanzhou,
Huang Kaiwen,
He Jianfeng
Publication year - 2021
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.202000125
Subject(s) - molecularly imprinted polymer , naringin , polymerization , adsorption , polymer , molecular imprinting , precipitation polymerization , chemistry , methacrylic acid , methacrylate , surface modification , coating , suspension polymerization , chromatography , chemical engineering , materials science , organic chemistry , radical polymerization , selectivity , catalysis , engineering
A facile strategy based on the boronate affinity and polydopamine coating was proposed for the preparation of surface molecularly imprinted polymer microspheres using naringin as the glycoside template. The poly(methacrylic acid‐co‐methyl methacrylate‐co‐ethyleneglycol dimethacrylate) microspheres were firstly synthesized as inner cores by suspension polymerization method, and then functionalized with 3‐aminophenylboronic acid. The imprinted shell layer was obtained by self‐polymerization of dopamine on the surface of boronic acid‐functionalized polymer microspheres after reversible immobilization of naringin. The resultant surface molecularly imprinted microspheres showed good imprinting efficiency and recognition specificity toward the template molecule in aqueous environment. The isothermal and kinetic adsorption behaviors of the polymers were investigated. The results showed that the covalent surface imprinted microspheres possessed homogeneous recognition sites, strong adsorption affinity, and rapid rebinding kinetics. In addition, the surface imprinted microspheres were utilized as the sorbents of solid phase extraction to successfully separate and enrich naringin from Citri Grandis extract, and the recovery of naringin in eluting solution reached 84.4%.