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Front Cover: A method based on precolumn derivatization and ultra high performance liquid chromatography with high‐resolution mass spectrometry for the simultaneous determination of phthalimide and phthalic acid in tea
Author(s) -
Gao Guanwei,
Chen Hongping,
Chai Yunfeng,
Jin Lili,
Liu Xin,
Lu Chengyin
Publication year - 2019
Publication title -
journal of separation science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201970071
Subject(s) - derivatization , chromatography , mass spectrometry , chemistry , phthalic acid , repeatability , resolution (logic) , phthalimide , extraction (chemistry) , analyte , high performance liquid chromatography , acetonitrile , organic chemistry , artificial intelligence , computer science
DOI: 10.1002/jssc.201801128 The cover picture shows an accurate method of determining phthalimide (PI) and phthalic acid (PA) in tea by acetonitrile extraction and 3‐bromopropyltrimethylammonium bromide derivatization coupled with ultraperformance liquid chromatography high resolution mass spectrometry. The method was validated, and satisfactory linearity, recovery, repeatability values were obtained. Then, the developed method was further successfully used to determine PI and PA in different tea matrices. All these observations provided crucial information and an analytical method to further study the sources and the related pathway of PI generation in tea.