Premium
Enantioselective separation and dissipation of pydiflumetofen enantiomers in grape and soil by supercritical fluid chromatography–tandem mass spectrometry
Author(s) -
Wu Xiuming,
Dong Fengshou,
Xu Jun,
Liu Xingang,
Wu Xiaohu,
Zheng Yongquan
Publication year - 2020
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201901332
Subject(s) - chromatography , chemistry , enantiomer , enantioselective synthesis , supercritical fluid chromatography , tandem mass spectrometry , mass spectrometry , resolution (logic) , analyte , supercritical fluid , detection limit , analytical chemistry (journal) , gas chromatography , organic chemistry , artificial intelligence , computer science , catalysis
Pydiflumetofen is registered in many countries and is widely used in crop production in the racemate form. However, the environmental behavior of the enantiomers has not been studied. An effective and sensitive chiral analytical method was first established for analyzing the pydiflumetofen enantiomers by supercritical fluid chromatography with tandem triple quadrupole mass spectrometry. The enantiomers could be separated and detected using the Chiralcel OD‐3 column in less than 3 min. The separation conditions were as follows: mobile phase, CO 2 /methanol (80:20); flow rate, 1.0 mL/min; column temperature, 30°C, auto back‐pressure regulator pressure, 2000 psi with modified quick, easy, cheap, effective, rugged, and safe sample treatment method. The average recoveries of analytes from both matrices at three spiking levels were in the range of 84.1–103.0%. The limit of quantitation for each enantiomer was 0.005 mg/kg with a baseline resolution of approximately 1.64. The method was applied to monitor the enantioselective dissipation of pydiflumetofen in grape and soil. In grapes, (−)‐pydiflumetofen was degraded more rapidly than (+)‐pydiflumetofen. In soil, (+)‐pydiflumetofen was preferentially degraded. The data provided useful references for the risk assessment and rational use of pydiflumetofen in agriculture.