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Metabolomics study of different parts of licorice from different geographical origins and their anti‐inflammatory activities
Author(s) -
Bai Haiying,
Bao Fang,
Fan Xiaorui,
Han Shu,
Zheng Wenhui,
Sun Lili,
Yan Na,
Du Hong,
Zhao Haiyu,
Yang Zhigang
Publication year - 2020
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201901013
Subject(s) - glycyrrhiza uralensis , metabolome , glycyrrhiza , metabolomics , traditional medicine , chemistry , tandem mass spectrometry , chromatography , mass spectrometry , medicine , alternative medicine , pathology
Glycyrrhiza uralensis Fisch., known as licorice, is one of the most famous traditional Chinese medicines. In this study, we perform a metabolome analysis using liquid chromatography–tandem mass spectrometry to assign bioactive components in different parts of licorice from different geographical origins in Gansu province of China. Sixteen potential biomarkers of taproots from different geographical origins were annotated, such as glycycoumarin, gancaonin Z, licoricone, and dihydroxy kanzonol H mainly exist in the sample of Jiuquan; neoliquiritin, 6′‐acetylliquiritin, licochalcone B, isolicoflavonol, glycyrol, and methylated uralenin mainly exist in Glycyrrhiza uralensis from Lanzhou; gancaonin L, uralenin, and glycybridin I mainly exist in licorice from Wuwei for the first time.