Premium
Supercritical fluid extraction in isolation of cyclitols and sugars from chamomile flowers
Author(s) -
AlSuod Hossam,
Ratiu IleanaAndreea,
KrakowskaSieprawska Aneta,
Lahuta Lesław,
Górecki Ryszard,
Buszewski Bogusław
Publication year - 2019
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201900539
Subject(s) - response surface methodology , supercritical fluid extraction , chromatography , supercritical fluid , chemistry , solvent , extraction (chemistry) , methanol , yield (engineering) , bar (unit) , box–behnken design , materials science , organic chemistry , composite material , physics , meteorology
Abstract The aim of the present study was to develop an optimization procedure for supercritical fluid extraction parameters, in order to obtain the highest possible yield of sugars and cyclitols from plant material. Response surface methodology based on Box‐Behnken design was applied to evaluate the effect of: temperature (40, 60, 80°C), pressure (100, 200, 300 bar), and co‐solvent (methanol) percentage (20, 25, 30%). As a result of the optimization process, we found that the highest amount of sugars (15.02 mg/gof dried material) and cyclitols (0.86 mg/g of dried material) was obtained when the following parameters were applied: 80°C, 228 bar, and 30% of methanol. Moreover, co‐solvent concentration and temperature had a higher influence onto the obtained amounts compared with the pressure.