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Back Cover: Selective enrichment of N‐linked glycopeptides and glycans by using a dextran‐modified hydrophilic material
Author(s) -
Chen Linlin,
Ding Di,
Sheng Qianying,
Yu Long,
Liu Xiuping,
Liang Xinmiao
Publication year - 2018
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201870092
Subject(s) - dextran , glycan , glycopeptide , chemistry , selectivity , ion exchange , chromatography , hydrophilic interaction chromatography , organic chemistry , biochemistry , ion , high performance liquid chromatography , glycoprotein , catalysis , antibiotics
J. Sep. Sci. 2018, 41 , 2003–2011 DOI: 10.1002//jssc.201700995 The cover picture shows the speculated mechanism of the interactions between the sialylated N‐glycans and the customized material named dextran–bonded silica during enrichment procedure. The hydrophilic and ion‐exchange interactions derived from the bonded dextran and the residual amino groups endow the material with high selectivity and coverage for acidic glycans and glycopeptides, which is very advantageous to their MS analysis.