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Selective separation and purification of β‐estradiol from marine sediment using an optimized core–shell molecularly imprinted polymer
Author(s) -
He Xiuping,
Lian Ziru,
Wang Jiangtao
Publication year - 2018
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201800722
Subject(s) - molecularly imprinted polymer , extraction (chemistry) , polymer , chromatography , adsorption , solid phase extraction , molecular imprinting , sediment , chemistry , materials science , selectivity , organic chemistry , geology , paleontology , catalysis
The core–shell molecularly imprinted polymers were optimized to provide reliable connections that allow molecularly imprinted polymers to be fixed on SiO 2 surface for the efficient separation and purification of β‐estradiol from marine sediment for the first time. To achieve the goal, different preparation methods were used and finally the polymer using 3‐methacryloxypropyltrimethoxysilane as coupling agent exhibited the best result, which further confirmed that 3‐methacryloxypropyltrimethoxysilane played an indispensable role on improving the inter‐particle connections. An offline molecularly imprinted solid‐phase extraction with high‐performance liquid chromatography method was successfully applied to the isolation and enrichment of β‐estradiol from marine sediment samples with high adsorption capacity, excellent clean‐up efficiency, and great enrichment effect as well as high recovery (>90%) and accuracy (RSD < 8.5%, n = 3). It proved the successful grafting of molecularly imprinted polymers on SiO 2 surface and the applicability of the offline molecularly imprinted solid‐phase extraction method in the selective extraction and enrichment of β‐estradiol from marine sediment.