Premium
Front Cover: Open tubular capillary column of 50 μm internal diameter with a very high separation efficiency for the separation of peptides in CEC and LC
Author(s) -
Ali Ashraf,
Cheong Won Jo
Publication year - 2017
Publication title -
journal of separation science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201770121
Subject(s) - column (typography) , chromatography , raft , polymerization , capillary action , fragmentation (computing) , chemistry , front cover , separation (statistics) , chain transfer , materials science , analytical chemistry (journal) , cover (algebra) , radical polymerization , polymer , geometry , composite material , computer science , mechanical engineering , organic chemistry , machine learning , engineering , operating system , mathematics , connection (principal bundle)
J. Sep. Sci . 2017, 40 , 2654–2661 DOI: 10.1002/jssc.201700242 The cover picture shows the performance of an open tubular silica capillary column of 50 μm id and 112 cm effective length fabricated by reversible addition‐fragmentation transfer (RAFT) polymerization. The column separation efficiency was over 1.7 million in CEC, and 286,700 in LC. The column was fabricated with a carefully formulated reaction mixture through elaborated procedures. Open tubular LC (OT‐LC) with a long column is one of the best choices in nanoLC‐MS analysis of peptides and proteins. This work enables to use open tubular columns of much better convenience (wider id, ca 50 μm) for such purpose.