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Front Cover: UHPLC–Q‐TOF‐MS‐based metabolomics approach to compare the saponin compositions of Xueshuantong injection and Xuesaitong injection
Author(s) -
Yao Changliang,
Yang Wenzhi,
Zhang Jingxian,
Qiu Shi,
Chen Ming,
Shi Xiaojian,
Pan Huiqin,
Wu Wanying,
Guo Dean
Publication year - 2017
Publication title -
journal of separation science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201770041
Subject(s) - panax notoginseng , protopanaxadiol , quadrupole time of flight , metabolomics , front cover , saponin , ginsenoside , chromatography , chemistry , mass spectrometry , significant difference , electrospray ionization , ginseng , cover (algebra) , medicine , mechanical engineering , alternative medicine , pathology , engineering
J. Sep. Sci . 2017, 40 , 834–841 DOI: 10.1002/jssc.201601122 The cover picture shows the discovery of the saponin difference between Xueshuantong Injection (XShTI) and Xuesaitong Injection (XSaTI) and the possible factor related to the chemical difference by ultra‐high performance liquid chromatography/quadrupole time‐of‐flight mass spectrometry based metabolomics. Wuzhou XShTI displays remarkable differentiation from the other products, with richer protopanaxatriol‐type noto‐R 1 , Rg 1 , Re and protopanaxadiol‐type Rb 1 , but less Rd and other low‐polarity protopanaxadiol‐type ginsenosides. Diverse preparation techniques, rather than the use of different parts of Panax notoginseng , may be the major factor leading to the observed chemical difference. The results are beneficial to the quality control of these Notoginseng total saponins products.