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Graphene‐based pipette tip solid‐phase extraction with ultra‐high performance liquid chromatography and tandem mass spectrometry for the analysis of carbamate pesticide residues in fruit juice
Author(s) -
Shi Zhihong,
Li Qi,
Xu Dan,
Huai Qingru,
Zhang Hongyi
Publication year - 2016
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201600498
Subject(s) - chromatography , chemistry , solid phase extraction , extraction (chemistry) , detection limit , sample preparation , mass spectrometry , tandem mass spectrometry , liquid chromatography–mass spectrometry , sorbent , adsorption , organic chemistry
Graphene‐based pipette tip solid‐phase extraction was combined with ultra‐high performance liquid chromatography and tandem mass spectrometry for the determination of carbamate pesticide residues in fruit juice samples. Four milligrams of graphene was used as sorbent material to pack a 1000 μL pipette tip for the extraction of pirimicarb, propoxur, isoprocarb, fenobucarb, and diethofencarb from 3 mL of fruit juice sample. The whole extraction process was finished in 12 min, and the volume of eluent used was only 1.5 mL. Under the optimized conditions, good linear relationship ( R > 0.999) and lower limits of detection (0.0022–0.033 ng/mL) were achieved. The recoveries at three spiked levels ranged from 80.90 to 124.60% with relative standard deviations less than 4.88%. Compared with commercially available sorbents including propylsulfonic acid silica, graphitized carbon black, and C 18 , graphene was superior in extraction efficiency. The proposed method is simple, rapid, sensitive, selective, and solvent saving.