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Core–shell SiO 2 ‐coated Fe 3 O 4 with a surface molecularly imprinted polymer coating of folic acid and its applicable magnetic solid‐phase extraction prior to determination of folates in tomatoes
Author(s) -
Areerob Yonrapach,
Sricharoen Phitchan,
Limchoowong Nunticha,
Chanthai Saksit
Publication year - 2016
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201600342
Subject(s) - tetraethyl orthosilicate , materials science , molecularly imprinted polymer , solid phase extraction , fourier transform infrared spectroscopy , scanning electron microscope , polymer , magnetite , analytical chemistry (journal) , detection limit , molecular imprinting , transmission electron microscopy , nuclear chemistry , chemical engineering , chromatography , chemistry , nanotechnology , organic chemistry , engineering , metallurgy , composite material , selectivity , catalysis
A novel core–shell magnetic surface molecularly imprinted polymer with folic acid as a template was successfully synthesized by the sol–gel method. To generate Lewis acid sites in the silica matrix for the interaction of the metal coordinate with the template, 3‐aminopropyltriethoxysilane was used as a functional monomer, tetraethyl orthosilicate as a cross‐linker, and aluminum ions as a dopant. The magnetite encapsulated by the silica shell plays an important role as a magnetic‐coated polymer. The synthesized product was characterized by powder X‐ray diffraction, scanning electron microscopy, transmission electron microscopy, and FTIR and UV/Vis spectroscopy. The powder X‐ray diffraction patterns, FTIR and UV/Vis spectra confirmed the characteristics of the as‐prepared silica coated magnetite and folic acid molecularly imprinted polymer. It was successfully applied for magnetic solid‐phase extraction prior to the determination of folates in tomato samples using high‐performance liquid chromatography with photodiode array detection. The detection limit of the proposed method was 1.67 μg/L, and results were satisfactory, with a relative standard deviation of < 3.94%.