Premium
Solid‐phase extraction based on chloromethylated polystyrene magnetic nanospheres followed by gas chromatography with mass spectrometry to determine phthalate esters in beverages
Author(s) -
Cao Xiaoji,
Kong Qiaoling,
Cai Ruonan,
Zhu Kundan,
Ye Xuemin,
Chen Jiaoyu,
Mo Weimin,
Wang Jianli
Publication year - 2014
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201400824
Subject(s) - phthalate , chromatography , chemistry , diethyl phthalate , solid phase extraction , extraction (chemistry) , polystyrene , detection limit , phthalic acid , dibutyl phthalate , gas chromatography–mass spectrometry , mass spectrometry , plasticizer , gas chromatography , desorption , adsorption , organic chemistry , polymer
An ultrasound‐assisted magnetic solid‐phase extraction procedure with chloromethylated polystyrene‐coated Fe 3 O 4 nanospheres as magnetic adsorbents has been developed to determine eight phthalate esters (bis(4‐methyl‐2‐pentyl) phthalate, dipentyl phthalate, dihexyl phthalate, benzyl butyl phthalate, bis(2‐butoxyethyl) phthalate, dicyclohexyl phthalate, di‐ n ‐octyl phthalate, and dinonyl phthalate) simultaneously in beverage samples, in combination with gas chromatography coupled to tandem mass spectrometry for the first time. Several factors related to magnetic solid‐phase extraction efficiencies, such as amount of adsorbent, extracting time, ionic strength, and desorption conditions were investigated. The enrichment factors of the method for the eight analytes were over 2482. A good linearity was observed in the range of 10–500 ng/L for bis(2‐butoxyethyl) phthalate and 2–500 ng/L for the other phthalate esters with correlation coefficients ranging from 0.9980 to 0.9998. The limits of detection and quantification for the eight phthalate esters were in the range of 0.20–2.90 and 0.67–9.67 ng/L, respectively. The mean recoveries at three spiked levels were 75.8–117.7%, the coefficients of variations were <11.6%. The proposed method was demonstrated to be a simple and efficient technique for the trace analysis of the phthalate esters in beverage samples.