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Hollow‐fiber liquid‐phase microextraction for the direct determination of flumequine in urban wastewaters by flow‐injection analysis with terbium‐sensitized chemiluminescence
Author(s) -
OcañaGonzález Juan Antonio,
RamosPayán María,
FernándezTorres Rut,
CallejónMochón Manuel,
BelloLópez Miguel Ángel
Publication year - 2014
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201400383
Subject(s) - flumequine , chemiluminescence , chromatography , detection limit , chemistry , extraction (chemistry) , terbium , flow injection analysis , fiber , solid phase microextraction , analytical chemistry (journal) , gas chromatography–mass spectrometry , mass spectrometry , ion , biochemistry , enrofloxacin , organic chemistry , ciprofloxacin , antibiotics
A flow‐injection analysis chemiluminescence method based on the enhancement effect of the flumequine‐Tb(III) complex on the weak native emission of the Ce(IV)‐Na 2 SO 3 system has been developed for the determination of flumequine. The method includes a cleanup and preconcentration stage (750‐fold) of the sample by hollow‐fiber liquid‐phase microextraction using an Accurel ® Q 3/2 polypropylene hollow fiber impregnated with 1‐octanol as the supported liquid membrane. The obtained 50 μL acceptor phase was injected in a 1 mM Tb(III) + 4 mM Ce(IV) in 5% v/v H 2 SO 4 stream and mixed with a 2 mM Na 2 SO 3 stream before its introduction into the flow cell. The chemiluminescence signal was linear in the 0.3–15 ng/mL range, with detection and quantitation limits of 0.1 and 0.3 ng/mL, respectively. The method allows the selective extraction and determination of flumequine in wastewater samples, using simpler and lower‐cost instrumentation and with shorter extraction and analysis times than traditional high‐performance liquid chromatography analysis.