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On‐line determination of 4‐nitrophenol by combining molecularly imprinted solid‐phase extraction and fiber‐optic spectrophotometry
Author(s) -
Muhammad Turghun,
Yimit Osmanjan,
Turahun Yunusjan,
Muhammad Kipayem,
Uludağ Yildiz,
Zhao Zhongkui
Publication year - 2014
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201400211
Subject(s) - molecularly imprinted polymer , chromatography , ethylene glycol dimethacrylate , solid phase extraction , analyte , extraction (chemistry) , detection limit , ethylene glycol , molecular imprinting , materials science , reproducibility , chemistry , polymer , monomer , selectivity , organic chemistry , methacrylic acid , catalysis , biochemistry , composite material
In the present paper, we describe a new on‐line SPE system where molecular imprinting, fiber‐optic detection and flow injection analysis were combined for the first time. This new system has been applied for the on line detection of 4‐nitrophenol (4‐NP). Initially, molecularly imprinted polymers (MIP) have been prepared for the selective extraction of 4‐NP using 4‐vinylpyridine and ethylene glycol dimethacrylate as functional and cross‐linking monomers, respectively. Selective extraction was achieved using the designed MIP with 97% of recovery on imprinted polymer and 10% on control polymer. The system provided a high degree of accuracy, with RSDs varying between 0.7 and 1.39%. In respect of accuracy, reproducibility, and rapidity, this system is comparable with HPLC. In short, the system allows simple, fast, and accurate analyte determination with the possibility of future automation.