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Gold nanoparticle decorated graphene oxide/silica composite stationary phase for high‐performance liquid chromatography
Author(s) -
Liang Xiaojing,
Wang Xusheng,
Ren Haixia,
Jiang Shengxiang,
Wang Licheng,
Liu Shujuan
Publication year - 2014
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201400005
Subject(s) - alkylbenzenes , graphene , hydrophilic interaction chromatography , phase (matter) , high performance liquid chromatography , reversed phase chromatography , oxide , mesoporous silica , chemistry , colloidal gold , nanoparticle , chromatography , silica gel , nucleobase , materials science , organic chemistry , nanotechnology , catalysis , mesoporous material , dna , biochemistry
In the initial phase of this study, graphene oxide (GO)/silica was fabricated by assembling GO onto the silica particles, and then gold nanoparticles (GNPs) were used to modify the GO/silica to prepare a novel stationary phase for high‐performance liquid chromatography. The new stationary phase could be used in both reversed‐phase chromatography and hydrophilic interaction liquid chromatography modes. Good separations of alkylbenzenes, isomerides, amino acids, nucleosides, and nucleobases were achieved in both modes. Compared with the GO/silica phase and GNPs/silica phase, it is found that except for hydrophilicity, large π‐electron systems, hydrophobicity, and coordination functions, this new stationary phase also exhibited special separation performance due to the combination of 2D GO with zero‐dimensional GNPs.