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Determination of bisphenol A in thermal printing papers treated by alkaline aqueous solution using the combination of single‐drop microextraction and HPLC
Author(s) -
Gao Leihong,
Zou Jing,
Liu Haihong,
Zeng Jingbin,
Wang Yiru,
Chen Xi
Publication year - 2013
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201201060
Subject(s) - chromatography , chemistry , aqueous solution , bisphenol a , drop (telecommunication) , organic chemistry , computer science , telecommunications , epoxy
A method for the quantitative determination of bisphenol A in thermal printing paper was developed and validated. Bisphenol A was extracted from the paper samples using 2% N a OH solution, then the extracted analyte was enriched using single‐drop microextraction followed by HPLC analysis. Several parameters relating to the single‐drop microextraction efficiency including extraction solvent, extraction temperature and time, stirring rate, and p H of donor phase were studied and optimized. Spiked recovery of bisphenol A at 20 and 5 mg/g was found to be 95.8 and 108%, and the method detection limit and method quantification limit was 0.03 and 0.01 mg/g, respectively. Under the optimized conditions, the proposed method was applied to the determination of bisphenol A in seven types of thermal printing paper samples, and the concentration of bisphenol A was found in the range of 0.53–20.9 mg/g. The considerably minimum usage of organic solvents (5 μL 1‐octanol) and high enrichment factor (189–197) in the sample preparation are the two highlighted advantages in comparison with previously published works.