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Loading behavior of gatifloxacin in urine and lake water on a novel magnetic molecularly imprinted polymer used as extraction sorbent with spectrophotometric analysis
Author(s) -
Dramou Pierre,
Xiao Deli,
He Hua,
Liu Tiebing,
Zou Wenyue
Publication year - 2013
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201200831
Subject(s) - molecularly imprinted polymer , sorbent , chromatography , extraction (chemistry) , polymer , detection limit , adsorption , chemistry , solid phase extraction , magnetic nanoparticles , molecular imprinting , fourier transform infrared spectroscopy , materials science , analytical chemistry (journal) , selectivity , chemical engineering , nanoparticle , organic chemistry , nanotechnology , engineering , catalysis
The loading behavior of gatifloxacin (GTFX) in human urine and lake water on a novel magnetic molecularly imprinted polymer used as extraction sorbent with UV‐Visible spectrometric analysis has been studied. The magnetic polymers had been prepared using GTFX as template molecule and Fe 3 O 4 as magnetic component. The polymer had been characterized by SEM, Fourier‐transform infrared spectrometry, and appropriate magnet separator. Parameters affecting the extraction efficiency were evaluated in order to achieve optimal loading and reduce nonspecific interactions. Good linearity of the method had been obtained in the range between 0.25 and 15 μg mL −1 by UV‐Vis spectrophotometry at 286 nm with spectral analysis from 240 to 400 nm. The method detection and quantification limits of GTFX in water were 0.075 and 0.25 μg mL −1 , respectively. This study showed good selectivity and loading efficiency (α > 2) of the polymers. The loading behavior of GTFX in the samples spiked on polymers had been obtained and each other with recovery higher than 91% with RSD% between 2.5 and 3.3. No pretreatment of samples were needed and no interference of compounds in urine and lake water were observed during adsorption.