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Selective silica‐based sorbent materials synthesized by molecular imprinting for adsorption of pharmaceuticals in aqueous matrices
Author(s) -
Morais Everton C.,
Correa Gabriel G.,
Brambilla Rodrigo,
dos Santos João Henrique Z.,
Fisch Adriano G.
Publication year - 2013
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201200774
Subject(s) - adsorption , molecular imprinting , chemistry , sorbent , aqueous solution , chromatography , selectivity , solid phase extraction , selective adsorption , nuclear chemistry , extraction (chemistry) , combinatorial chemistry , organic chemistry , catalysis
The presence of pharmaceuticals in aqueous environmental matrices often requires efficient and selective preconcentration procedures. Thus, silicas (SILs) were synthesized by a molecular imprinting technique using an acid‐catalyzed sol‐gel process and the following drugs as templates: fluoxetine, gentamicin, lidocaine, morphine, nifedipine, paracetamol, and tetracycline. The materials were subjected to sorbent extraction assisted by ultrasonic treatment to remove the drugs and the consequent formation of molecular imprinted cavities. The surface area of the resulting materials ranged from 290 to 960 m 2 /g. Adsorption tests were performed with the molecular imprinting phases. In terms of the potential selectivity, the SILs were subjected to the adsorption of drugs from samples such as potable and surface water. The adsorption capacity remained in the range between 55 and 65% for both matrices, while for the nonimprinted SIL it remained between 15 and 20%.