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Separation, interconversion, and insecticidal activity of the cis‐ and trans ‐isomers of novel hydrazone derivatives
Author(s) -
Wu Jian,
Huang Chaoqun,
Wang Jian,
Hu Deyu,
Jin Linhong,
Yang Song,
Song Baoan
Publication year - 2013
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201200693
Subject(s) - hydrazone , chemistry , cis–trans isomerism , isomerization , structural isomer , high performance liquid chromatography , medicinal chemistry , stereochemistry , chromatography , organic chemistry , catalysis
A series of cis ‐ and trans ‐isomers of hydrazone derivatives were separated and analyzed through HPLC with diode‐array detection and HPLC ‐ MS / MS using ESI and ion trap MS . Two single crystals ( A ‐5‐1 and C ‐2‐1) of the trans ‐isomers were obtained and determined using X ‐ray crystallography data, and the cis ‐ to trans ‐isomerization under different conditions was discussed. Both of the cis ‐ and trans ‐isomers of A ‐4 and A ‐5 exhibited good insecticidal activities against P lutella xylostella .