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Evaluation of matrix solid‐phase dispersion extraction for the determination of polycyclic aromatic hydrocarbons in household dust with the aid of experimental design and response surface methodology
Author(s) -
Christopoulou Ourania D.,
Sakkas Vasilios A.,
Albanis Triantafyllos A.
Publication year - 2012
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201200563
Subject(s) - chromatography , extraction (chemistry) , analyte , matrix (chemical analysis) , solid phase extraction , solvent , dispersion (optics) , elution , dispersant , response surface methodology , chemistry , sample preparation , detection limit , analytical chemistry (journal) , mass spectrometry , physics , organic chemistry , optics
A simple, fast, and inexpensive procedure for sample preparation based on matrix solid‐phase dispersion was developed for the determination of E nvironmental P rotection A gency 16 priority polycyclic aromatic hydrocarbons in indoor dust samples. Parameters that affect the extraction efficiency such as type of dispersant, elution solvent, and solvent volume were evaluated and optimized with the aid of experimental design and response surface methodology. Analysis was performed by HPLC coupled with UV ‐ V is diode array detector (UV‐DAD). For verification, a GC coupled with a mass spectrometer in SIM mode was also applied. Recoveries obtained were from 53 to 120% for all target analytes with detection limits ranging from 0.2 to 10 ng/g and 0.2 to 2 ng/g for LC ‐ UV ‐DAD and GC ‐ MS , respectively. The optimized method was used for the analysis of 11 household dust samples collected from private houses.