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Determination of bromate in drinking water by ultraperformance liquid chromatography–tandem mass spectrometry
Author(s) -
Alsohaimi Ibrahim Hotan,
Alothman Zeid Abdullah,
Khan Mohammad Rizwan,
Abdalla Mohammad Abulhassan,
Busquets Rosa,
Alomary Ahmad Khodran
Publication year - 2012
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201200312
Subject(s) - bromate , chemistry , chromatography , detection limit , bottled water , mass spectrometry , repeatability , liquid chromatography–mass spectrometry , bromide , tandem mass spectrometry , environmental science , organic chemistry , environmental engineering
Bromate is a byproduct formed as a result of disinfection of bromide‐containing source water with ozone or hypochlorite. The International Agency for Research on Cancer has recognized bromate as a possible human carcinogen, thus it is essential to determine in drinking water. Present work highlights a development of sensitive and fast analytical method for bromate determination in drinking water by using ultraperformance liquid chromatography–tandem mass spectrometry. The quality parameters of the developed method were established, obtaining very low limit of detection (0.01 ng/mL), repeatability and reproducibility have been found to be less than 3% in terms of relative standard deviation when analyzing a bromate standard at 0.05 μg/mL with 0.4 min analysis time. Developed method was applied for the analysis of metropolitan and bottled water from Saudi Arabia; 22 samples have been analyzed. Bromate was detected in the metropolitan water samples (from desalinization source) at concentrations ranging between 3.43 and 75.04 ng/mL and in the bottled water samples at concentrations ranging between 2.07 and 21.90 ng/mL. Moreover, in comparison to established analytical methods such as liquid chromatography–tandem mass spectrometry, the proposed method was found to be very sensitive, selective and rapid for the routine analysis of bromate at low level in drinking water.