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Quantitative analysis of perfumes in talcum powder by using headspace sorptive extraction
Author(s) -
Ng Khim Hui,
Heng Audrey,
Osborne Murray
Publication year - 2012
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201100918
Subject(s) - solid phase microextraction , chromatography , repeatability , extraction (chemistry) , sample preparation , gas chromatography , analyte , chemistry , analytical chemistry (journal) , mass spectrometry , gas chromatography–mass spectrometry , materials science
Quantitative analysis of perfume dosage in talcum powder has been a challenge due to interference of the matrix and has so far not been widely reported. In this study, headspace sorptive extraction ( HSSE ) was validated as a solventless sample preparation method for the extraction and enrichment of perfume raw materials from talcum powder. Sample enrichment is performed on a thick film of poly(dimethylsiloxane) ( PDMS ) coated onto a magnetic stir bar incorporated in a glass jacket. Sampling is done by placing the PDMS stir bar in the headspace vial by using a holder. The stir bar is then thermally desorbed online with capillary gas chromatography‐mass spectrometry. The HSSE method is based on the same principles as headspace solid‐phase microextraction ( HS ‐ SPME ). Nevertheless, a relatively larger amount of extracting phase is coated on the stir bar as compared to SPME . Sample amount and extraction time were optimized in this study. The method has shown good repeatability (with relative standard deviation no higher than 12.5%) and excellent linearity with correlation coefficients above 0.99 for all analytes. The method was also successfully applied in the quantitative analysis of talcum powder spiked with perfume at different dosages.