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Identification of ionic liquid components by RP‐HPLC with diode array detector using chaotropic effect and perturbation technique
Author(s) -
Flieger Jolanta,
CzajkowskaŻelazko Anna
Publication year - 2012
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201100751
Subject(s) - chemistry , chaotropic agent , ionic liquid , hexafluorophosphate , acetonitrile , reagent , tetrafluoroborate , high performance liquid chromatography , chromatography , ion , selectivity , chromatography detector , ionic bonding , resolution (logic) , analytical chemistry (journal) , organic chemistry , catalysis , artificial intelligence , computer science
Sodium hexafluorophosphate, perchlorate and tetrafluoroborate were applied as the ion‐pair reagents in reversed‐phase chromatography of several imidazolium‐based ionic liquids. The optimization of the retention was performed by changing the kind of organic modifier (methanol, acetonitrile), concentration and the kind of the ion‐pair reagents in the mobile phase and the column kind (Zorbax SB‐C18, Zorbax SB‐Phenyl, Zorbax SB‐CN, Zorbax SB‐NH 2 and Supelcosil LC‐F). The selectivity of the proposed chromatographic systems according to the cation kind was compared on the basis of the resolution of ionic liquid mixture. The perturbation method was applied to identify the anion kind. The formation of ion‐associated complexes between promethazine as counter‐cation and chaotropic anions controlling their retention was confirmed.