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Preparation and selective recognition of a novel solid‐phase microextraction fiber combined with molecularly imprinted polymers for the extraction of parabens in soy sample
Author(s) -
He Juan,
Chen Si,
Jiang Yili,
Shen Yanzheng,
Zhu Jing,
Wei Hongliang,
Zhang Hongxia,
Lu Kui
Publication year - 2012
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201100721
Subject(s) - solid phase microextraction , molecularly imprinted polymer , chromatography , extraction (chemistry) , detection limit , solid phase extraction , fiber , polymer , chemistry , sample preparation , materials science , selectivity , gas chromatography–mass spectrometry , mass spectrometry , organic chemistry , catalysis
A prepared molecularly imprinted polymer with ethyl p ‐hydroxybenzoate as template molecule was applied for the first time to a homemade solid‐phase microextraction fiber. The molecularly imprinted polymer‐coated solid‐phase microextraction fiber was characterized by scanning electron microscopy and thermogravimetric analysis. Various parameters were investigated, including extraction temperature, extraction time, and desorption time. Under the optimum extraction conditions, the molecularly imprinted polymer‐coated solid‐phase microextraction fiber exhibited higher selectivity with greater extraction capacity toward parabens compared with the nonimprinted polymer‐coated solid‐phase microextraction fiber and commercial fibers. The molecularly imprinted polymer‐coated solid‐phase microextraction fiber was tested using gas chromatography to determine parabens, including methyl p ‐hydroxybenzoate, ethyl p ‐hydroxybenzoate, and propyl p ‐hydroxybenzoate. The linear ranges were 0.01–10 μg/mL with a correlation coefficient above 0.9943. The detection limits (under signal‐to‐noise ratio of 3) were below 0.30 μg/L. The fiber was successfully applied to the simultaneous analysis of three parabens in spiked soy samples with satisfactory recoveries of 95.48, 97.86, and 92.17%, respectively. The relative standard deviations ( n =6) were within 2.83–3.91%. The proposed molecularly imprinted polymer‐coated solid‐phase microextraction method is suitable for selective extraction and determination of trace parabens in food samples.