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Determination of parabens in cosmetic products by solid‐phase microextraction of poly(ethylene glycol) diacrylate thin film on fibers and ultra high‐speed liquid chromatography with diode array detector
Author(s) -
Fei Ting,
Li Haifang,
Ding Mingyu,
Ito Masahito,
Lin JinMing
Publication year - 2011
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201100225
Subject(s) - solid phase microextraction , propylparaben , chromatography , methylparaben , fiber , materials science , ethylene glycol , detection limit , molecularly imprinted polymer , paraben , extraction (chemistry) , polymer , chemistry , gas chromatography–mass spectrometry , mass spectrometry , organic chemistry , preservative , composite material , selectivity , catalysis
The fabrication of a solid‐phase microextraction (SPME) fiber through UV‐induced polymerization of poly(ethylene glycol) diacrylate (PEG‐DA) for determination of parabens in cosmetic products is presented in this work. The PEG‐DA polymer coating was covalently attached to the fiber by introducing a surface modification with 3‐(trichlorosilyl)propyl methacrylate (TPM). The PEG‐DA polymer thin film coated on the fiber was homogeneous and wrinkled, which led to an increase of the surface area and high extraction efficiency. The extraction performances of the prepared SPME fibers were assessed by preconcentration of parabens including methylparaben, ethylparaben, propylparaben and benzylparaben from cosmetic products. The analysis was performed on an ultra high‐speed liquid chromatography with diode array detector. The prepared SPME fibers exhibited good repeatability (for one fiber) and reproducibility (fiber‐to‐fiber) with RSDs of 5.4 and 6.9%, respectively. The optimized SPME method supported a wide linear range of 0.50–160 μg/mL and the detection limits for parabens were in the range of 0.12–0.15 μg/mL ( S / N =3). The developed method was successfully applied for determination of parabens in cosmetic products with different natures.