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Examination of the surface heterogeneity of reversed‐phase packing materials with solvent adsorption
Author(s) -
Vajda Péter,
Bocian Szymon,
Buszewski Bogusław,
Felinger Attila
Publication year - 2010
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.201000341
Subject(s) - silanol , adsorption , chemistry , elution , acetonitrile , aqueous solution , solvent , phase (matter) , chromatography , reversed phase chromatography , aqueous two phase system , high performance liquid chromatography , organic chemistry , catalysis
The adsorption isotherms of acetonitrile, ethanol, 2‐propanol, and THF were measured using frontal analysis on six columns packed with octadecyl RP stationary phase. The effect of the bonding density of the end‐capped octadecyl bonded phase on the adsorption properties was measured. Adsorption isotherm data were collected from aqueous solutions of the four organic modifiers. The isotherm model for solvent adsorption was selected using two independent parameter estimation methods, the regression analysis and adsorption energy distribution. The fitted isotherm parameters were tested by modeling of overloaded elution bands with the aid of the equilibrium‐dispersive model of chromatography. The surface heterogeneity estimations and the effect of the silanol groups on the adsorption of solvents were based on those data.