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Chromatographic fingerprinting and related chemometric techniques for quality control of traditional Chinese medicines
Author(s) -
Liang Yizeng,
Xie Peishan,
Chau Footim
Publication year - 2010
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200900653
Subject(s) - chemometrics , quality (philosophy) , computer science , fingerprint (computing) , biochemical engineering , quality by design , chemistry , artificial intelligence , machine learning , engineering , philosophy , epistemology , particle size
Development of chromatographic fingerprint (CF) and related chemometric methods and their applications to quality control of traditional Chinese medicines (TCMs) were discussed. CF is essentially a kind of quality control method for TCMs (or Chinese herbal medicines). Also, it is a quality‐relevant‐data high‐throughput and integral tool to explore chemically the complexity of TCMs. With the help of chemometrics, some difficulties in evaluation and analysis of CFs, such as calculation of information content, peak alignment, pattern analysis, deconvolution of overlapping peaks, etc. could be well solved. To further explore TCMs synergic quality, intensive study of CF coupled with chemometrics will create the possibility to achieve the aim to reveal the working mechanisms of TCMs and to further control and strengthen TCMs' intrinsic quality in a comprehensive manner.