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Studies towards enantioselective surface imprinted polymers
Author(s) -
Yilmaz Ecevit,
Billing Johan,
Boyd Brian,
Möller Per,
Rees Anthony
Publication year - 2009
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200900236
Subject(s) - template , molecularly imprinted polymer , polymer , enantiomer , molecular imprinting , enantioselective synthesis , monomer , combinatorial chemistry , materials science , molecule , nanotechnology , chemistry , organic chemistry , selectivity , catalysis
Molecularly imprinted polymers (MIPs) are tailor‐made materials that can specifically rebind desired target molecules. Usually, the template is in solution with monomers that form a specific polymeric cavity around the template. Here, a model system with an amino acid (Fmoc‐ L ‐Histidine) is presented. This new approach entails the imprinting of templates that are bound to support materials. It is shown that the new approach leads to materials that exhibit symmetric peak shapes for both enantiomers under isocratic conditions.