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Transverse diffusion of laminar flow profiles – a generic method for mixing reactants in capillary microreactor
Author(s) -
Krylova Svetlana M.,
Okhonin Victor,
Krylov Sergey N.
Publication year - 2009
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200800671
Subject(s) - microreactor , laminar flow , capillary action , mixing (physics) , diffusion , laminar flow reactor , chemistry , flow (mathematics) , chromatography , analytical chemistry (journal) , materials science , chemical engineering , mechanics , thermodynamics , organic chemistry , open channel flow , catalysis , physics , quantum mechanics , engineering , composite material
The capillary is an attractive format for integrated microanalyses, which start with the injection of separate reactants into the capillary and their mixing inside the capillary. Due to the nonturbulent nature of flow inside the capillary, mixing reactants in a generic way is a challenging task. Three approaches have been suggested as a solution: mixing by electrophoresis, mixing by longitudinal diffusion, and, most recently, mixing by transverse diffusion of laminar flow profiles (TDLFP). This is the first review on TDLFP, describing: (i) the physical basis of the method, (ii) its theory, (iii) analytical and numerical solutions for the calculation of concentration profiles of mixed reactants, (iv) up‐to‐date applications, and (v) problems to be solved and future directions.