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Stop‐flow comprehensive two‐dimensional gas chromatography with pneumatic switching
Author(s) -
Oldridge Nathan,
Panic Ognjen,
Górecki Tadeusz
Publication year - 2008
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200800265
Subject(s) - flow (mathematics) , chromatography , dimension (graph theory) , two dimensional gas , sensitivity (control systems) , resolution (logic) , chemistry , volumetric flow rate , gas chromatography , two dimensional chromatography , analytical chemistry (journal) , mechanics , mathematics , computer science , artificial intelligence , physics , engineering , electronic engineering , pure mathematics
A new method for performing comprehensive GC×GC in the stop‐flow mode is presented. A device was used to pneumatically stop the flow in the first dimension ( 1 D) (by applying pressure pulses at the junction between the two columns), while flow was maintained in the second dimension ( 2 D). This allowed for better preservation of resolution in the 1 D of the GC×GC chromatograms, and the extension of the 2 D's separation space, reducing or eliminating the extent of wraparound. When increased flow rates in the 2 D were used, sensitivity enhancements were also observed.