Premium
Determination of radix ginseng volatile oils at different ages by comprehensive two‐dimensional gas chromatography/time‐of‐flight mass spectrometry
Author(s) -
Qiu Yaqiong,
Lu Xin,
Pang Tao,
Ma Chenfei,
Li Xiang,
Xu Guowang
Publication year - 2008
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200800253
Subject(s) - ginseng , chemistry , chromatography , flame ionization detector , gas chromatography–mass spectrometry , gas chromatography , mass spectrometry , radix (gastropod) , kovats retention index , botany , medicine , alternative medicine , pathology , biology
Comprehensive 2‐D GC (GC×GC) coupled with TOF MS or flame ionization detector (FID) was employed to characterize and quantify the chemical composition of volatile oil in the radixes of Panax ginseng C. A. Mey. (ginseng) at different ages. Thirty‐six terpenoids were tentatively identified based on the MS library search and retention index in a ginseng sample at the age of 3 years. An obvious group‐type separation was obtained in the GC×GC‐TOF MS chromatogram. The data collected by GC×GC‐FID were processed using a principal component analysis (PCA) method to classify the samples at different ages. The compounds responsible for the significant differentiation among samples were defined. It was found that the relative abundances of α‐cadinol, α‐bisabolol, thujopsene, and n ‐hexadecanoic acid significantly rise with the increase in age.