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Capillary gas chromatographic analysis of pyrrolidinedithiocarbamate metal chelates
Author(s) -
Laghari Abdul J.,
Khuhawar Muhammad Y.,
Zardari Liaquat A.
Publication year - 2007
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200700264
Subject(s) - chemistry , chelation , metal , detection limit , gas chromatography , chromatography , analytical chemistry (journal) , nuclear chemistry , inorganic chemistry , organic chemistry
Pyrrolidinedithiocarbamate (PDTC) chelates of Zn(II), Cu(II), Ni(II), Co(III), Fe(III), Mn(II), Cr(III), and VO(II) were analysed by capillary GC on a DB‐1701 column (30 m×0.25 mm id) with flame ionisation detection (FID). Linear calibrations were attained within “1–30 μg/mL” for Ni(II), Fe(III), Mn(II), Cr(III), Cu(II), and VO(II), and within “2–50 μg/mL” for Co(III) and Zn(II). The limits of detection were in the “150–500 ng/mL” range, corresponding to 15–50 pg amounts reaching the FID system. The optimised method was applied to the determination of Cu(II) and Ni(II) in coins, and that of Zn(II), Cu(II), Ni(II), Fe(III), Mn(II), Cr(III), and VO(II) in pharmaceutical preparations with relative standard deviations within 1.1–5.2%. The results obtained are in good agreement with sewage water samples and the declared values for the pharmaceutical formulations, or with the results of AAS of metal contents in coins, pharmaceutical preparations, and sewage water samples.