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Electrochromatographic separation on a poly(dimethylsiloxane)/glass chip by integration of a capillary containing an acrylate monolithic stationary phase
Author(s) -
Blas Maximilien,
Delaunay Nathalie,
Rocca JeanLouis
Publication year - 2007
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200700132
Subject(s) - capillary electrochromatography , electrochromatography , acrylate , capillary action , materials science , phase (matter) , stationary phase , chip , chromatography , chemistry , polymer , composite material , copolymer , computer science , organic chemistry , telecommunications
Abstract In this paper, we present an approach to perform electrochromatographic separations on poly(dimethylsiloxane) chips: a fused‐silica capillary containing a stationary phase was introduced directly into the chip. This approach would offer great flexibility since capillary modification methods are well known, and thus, with this kind of chip, different microfluidic devices having various functionalizations could be prepared. Electrophoretic separations were first achieved by integrating an empty capillary into the chip to evaluate the analytical performances of this system. They were compared to those obtained with a classical chip. Finally, an electrochromatographic separation involving a capillary containing a hexyl acrylate‐based monolith was performed. These preliminary results show this approach to be promising.