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Developments in ion chromatography using monolithic columns
Author(s) -
Chambers Stuart D.,
Glenn Karen M.,
Lucy Charles A.
Publication year - 2007
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200700090
Subject(s) - monolith , monolithic hplc column , ion chromatography , polyelectrolyte , ionic bonding , column chromatography , coating , covalent bond , reagent , materials science , chromatography , ion exchange , chemistry , ion , nanotechnology , polymer , high performance liquid chromatography , organic chemistry , catalysis
The focus of this review is on current status and on‐going developments in ion chromatography (IC) using monolithic phases. The use and potential of both silica and polymeric monoliths in IC is discussed, with silica monoliths achieving efficiencies upwards of 10 5 plates/m for inorganic ions in a few minutes or less. Ion exchange capacity can be introduced onto the monolithic columns through the addition of ion interaction reagents to the eluent, coating of the monolith with ionic surfactants or polyelectrolyte latexes, and covalent bonding. The majority of the studies to date have used surfactant‐coated columns, but the stability of surfactant coatings limits this approach. Applications of monolithic IC columns to the separation of inorganic anions and cations are tabulated. Finally, a discussion on the recent commercialization of monolithic IC columns and the use of monolithic phases for IC peripherals such as preconcentrator columns, microextractors and suppressors is presented.