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Rapid and sensitive determination of two degradation products of flumethrin in honey by ultrasonically assisted extraction and gas chromatography with electron capture detection
Author(s) -
Zhou Jinhui,
Xue Xiaofeng,
Li Yi,
Zhang Jinzhen,
Wu Liming,
Chen Lanzhen,
Zhao Jing
Publication year - 2007
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200700023
Subject(s) - chromatography , gas chromatography , electron capture detector , extraction (chemistry) , chemistry , degradation (telecommunications) , electron capture , computer science , organic chemistry , ion , telecommunications
A rapid and sensitive method for the determination of 4‐fluoro‐3‐phenoxybenzaldehyde cyanohydrin (FPBC) and 4‐fluoro‐3‐phenoxy‐benzaldehyde (FPB) in honey samples using ultrasonically assisted extraction and gas chromatography with electron capture detection (GC–ECD) has been developed. The different factors affecting the efficiency of the extraction were carefully optimized. The honey sample was extracted with a mixture of hexane and dichloromethane (v/v, 1:1) utilizing the ultrasonically assisted technique and cleaned up by solid‐phase extraction on Oasis HLB cartridges. The eluate was evaporated to dryness and residues were reconstituted to 1.0 mL with hexane and determined by GC–ECD. The calibration curves of fortified samples showed acceptable linear response ( R 2 >0.99) over a range of 3–100 ng/g for FPBC and FPB in seven replicate determinations of six concentrations, respectively, and analysis of variance (ANOVA) with a lack‐of‐fit test was performed to validate the regression data. Overall average recoveries ranged from 90.9 to 106.2% for honey samples. The detection limits were 0.9 ng/g for FPBC and 1.0 ng/g for FPB, respectively. This method can be successfully applied to routine determination of two degradation products of flumethrin in honey samples.