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Microfluidic selection and applications of aptamers
Author(s) -
Mosing Renee K.,
Bowser Michael T.
Publication year - 2007
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200600483
Subject(s) - aptamer , microfluidics , systematic evolution of ligands by exponential enrichment , nanotechnology , chemistry , computational biology , chromatography , biology , materials science , microbiology and biotechnology , biochemistry , rna , gene
The high affinity and specificity of aptamers make them ideal reagents for a wide range of analytical applications. It is not surprising that they are finding application in microfluidics as well. CE has proven to be an efficient technique for isolating aptamers. Aptamers have been used as affinity reagents in CE assays. Aptamer‐based chromatography stationary phases have demonstrated unique selectivities. Possibly the application that holds the highest potential is aptamer microarrays for screening proteomic samples.