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Direct enantiomeric separations of tris(2‐phenylpyridine) iridium (III) complexes on polysaccharide derivative‐based chiral stationary phases
Author(s) -
Chen Xiaoming,
Okamoto Yoshio,
Yano Tomohiro,
Otsuki Joe
Publication year - 2007
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200600409
Subject(s) - chemistry , enantiomer , iridium , cellulose , hexane , elution , column chromatography , chromatography , tris , derivative (finance) , high performance liquid chromatography , organic chemistry , catalysis , biochemistry , financial economics , economics
A convenient method is presented for the first time for the direct separation of enantiomers of a tris(2‐phenylpyridine) iridium (III) and an analog substituted with long alkoxy chains on polysaccharide derivative‐based chiral stationary phases by HPLC. Tris(2‐phenylpyridine) iridium (III) was separated on the immobilized amylose 3,5‐dimethylphenylcarbamate (Chiralpak IA) using hexane/CHCl 3 /CH 2 Cl 2 (75:20:5) as an eluent, and the analog could be separated on the coated cellulose 3,5‐dimethylphenylcarbamate (Chiralcel OD) and cellulose 4‐methylbenzoate (Chiralcel OJ) using hexane/2‐propanol (96:4) as the eluent. CD spectra of the eluted HPLC fractions were also recorded, and the observed mirror image patterns confirm their enantioseparations.