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Gas chromatography‐mass spectrometry following pressurized hot water extraction and solid‐phase microextraction for quantification of eucalyptol, camphor, and borneol in Chrysanthemum flowers
Author(s) -
Dong Ling,
Wang Jiyao,
Deng Chunhui,
Shen Xizhong
Publication year - 2007
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200600207
Subject(s) - eucalyptol , borneol , camphor , solid phase microextraction , chromatography , chemistry , extraction (chemistry) , gas chromatography–mass spectrometry , mass spectrometry , gas chromatography , solid phase extraction , chemometrics , essential oil , traditional chinese medicine , organic chemistry , medicine , alternative medicine , pathology
Abstract Chrysanthemum flower is a common traditional Chinese medicine (TCM). In this work, pressurized hot water extraction (PHWE) followed by headspace solid‐phase microextraction (HS‐SPME) and GC‐MS was developed for the determination of three main active volatile compounds of eucalyptol, camphor, and borneol in Chrysanthemum flowers from four different growing areas in China by internal standard method. The parameters of PHWE and HS‐SPME were optimized. The method was also validated. The results showed that PHWE‐SPME‐GC‐MS is a simple, rapid, efficient, and solvent‐free technique for the quantitative determination of eucalyptol, camphor, and borneol in TCMs and is potentially useful for the TCM quality assessment.